SKOAP Study FAQ
What is SKOAP?
The Sequenced strategy for improving outcomes in people with Knee OsteoArthritis Pain (SKOAP) study will compare treatments with the goal of reducing KOA pain and improving function. It is a national study, funded by the Helping to End Addiction Long-term Initiative, or NIH HEAL Initiative, that will find out what treatments work best for which patients.
SKOAP is comparing widely used non-opioid pain treatments to reduce knee pain and improve knee function. In the first part of the study, participants will be treated with conservative therapies and, in the second part, they will be treated with non-surgical procedures.
Who is running the study?
The SKOAP trial is a collaborative project between the National Institutes of Health (NIH), Johns Hopkins, Duke, Utah, Vanderbilt and all of our participating clinical centers.
Why is the SKOAP study important?
Knee osteoarthritis (KOA) is a very common source of pain and reduced function. There is an urgent public health need to reduce our reliance on opiods for effective long-term pain management, particularly in knee osteoarthritis (KOA).
This effectiveness trial will compare recommended treatments to reduce pain and functional limitations in KOA and identify clinical and patient-level factors associated with treatment response.
These results will lead to improved patient selection for treatment and inform evidence-based guidelines by offering well-tested, effective, non-opioid alternatives.
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How long does the study last?
Phase 1 is 8 weeks with follow-up for up to 2 years. Phase 2 is 12 weeks with follow-up for up to one year. Candidates may advance from Phase 1 to Phase 2 if eligible at any time after the 8-week visit.
What is the compensation for the study?
Compensation up to $742 - depending on eligibility and study visits/tasks completed. Parking coupon/pass is provided at all sites.
Does my insurance pay for the treatments?
Most insurance companies approve and cover our study procedures. Phase 1 treatments are commonly used for knee pain and usually do not require pre-authorization. Phase 2 treatments usually do require pre-authorization. For both phases, there may be a copay that candidates will be responsible for.
That said, insurance coverage does vary by region and company. For questions, call the project coordinator at the closest SKOAP site using the contact information on the About Us page.
Are any of the treatments experimental?
No, all of the treatments in this study are considered standard of care, which means that they are all widely used and accepted forms of treatment for Knee Osteoarthritis.
We take a systematic approach to your treatment and offer some treatments that may be hard to get elsewhere. Research staff can answer more specific questions about the treatments we are studying.
I am uncomfortable with coming in person due to the pandemic - can the study be done virtually?
Only one in-person study visit is required during Phase 2, which includes knee injections or nerve procedures. All other study visits can be done virtually via telemedicine appointments with study staff.